Stem Cell Therapy
Stem Cell Therapy is also called Regenerative medicine. Stem Cell Therapy encourages the repair response of injured tissues, diseased tissue or dysfunctional tissue using stem cells.
The success rate of Stem Cell Therapy
The stem cell treatment has gained popularity significantly due to its effectiveness and high success rate up to 70 to 80%. This is due to the most advanced and latest regenerative medical treatment that uses a biological component that is stem cells.
This therapy also comes with negative effects such as treatment some patients have come up with problems such as Mucositis, Nausea, vomiting etc.
Types of Stem Cell
- Primarily there are five types of Stem Cell
- Totipotency or Toti-Total – It is the ability of a single cell to divided and produce all of the differentiated cells in an organism.
- Pluripotency or Pluri-several refers to a stem cell that has the potential to differentiate into any of the three germ layers-ectoderm, endoderm, and mesoderm.
- Multipotency or multi-many refers to the stem cell that can differentiate into various types of cells that are related.
- Example – Blood stem cells can differentiate into lymphocytes, monocytes, Neutrophils etc.
- Oligopotency or Oligo-Few refers to stem cells that can differentiate into few cell types.
- For Example Lymphoid or Myeloid stem cells can differentiate into B and T cells but not RBC.
- Unipotency or Uni-Single refers to the ability of the stem cells to differentiate into only one cell type.
Stem Cells Technology
The stem cell might come from the donor or the patient themselves.
The stem cell is undifferentiated cells found in most multicellular animals. These cells maintain their undifferentiated state even after undergoing numerous mitotic divisions.
It also has the potential to revolutionize the future of medicine with the ability to regenerate damaged and diseased organs.
Also, it is capable of self-renewal and exhibits ‘Cellular Potency’.
Differentiation of Stem Cells
The stem cell is differentiated into all types of cells, which are derived from any three germ layers such as ectoderm, endoderm, and mesoderm.
Mammals have two main types of stem cells. They are embryonic stem cells (ES Cells) and Adult Stem Cells.
Embryonic Stem Cells
- ES cells are pluripotent and can produce all three germ layers.
- ES cells are isolated from the Epiblast tissue of the inner cell mass of a blastocyst.
- When stimulated ES can develop into more than 200 cell types of the adult body.
- ES cells are immortal that is they can proliferate in a sterile culture medium and maintain their undifferentiated state.
Adult Stem Cells
- Adult stem cells are found in various tissues of children as well as adults.
- An adult stem cell or somatic stem cell can divide and create another cell similar to it.
- Most adult stem cells or somatic stem cells can divide and create another cell similar to it.
- Most of the adult stem cells are multipotent and can act as a repair system of the body, replenishing adult tissues.
- The red bone marrow is a rich source of adult stem cells.
The most important and potential application of human stem cells is the generation of cells and tissues that could be used for cell-based therapies. Human stem cells could be used to test new drugs.
Conditions commonly treated are Knee, blood cancers, burns, damaged corneas, Autism, etc. However, there is no clear scientific evidence that supports the best type of stem cell therapy for autism and it is not recommended as therapy for Autism.
The type of cancer currently used in stem cell therapy are leukaemia and lymphoma. This may also be used for neuroblastoma and multiple myeloma. Other types of cancer, that involve cell transplants are under study in clinical trials.
Stem cell Therapy Cure List
- Spinal Cord Injuries
- Type 1 Diabetes
- Parkinson’s Disease
- Amyotrophic Lateral Sclerosis
- Alzheimer’s Disease
- Heart Disease
Stem cell Banks
- Stem cell Banks are the extraction, processing, and storage of stem cells.
- These will be used for treatment in the future.
- An amniotic cell bank is a facility that stores stem cells derived from amniotic fluid for future use.
- Stem cells are stored in banks specifically for use by the individual from whom such cells have been collected and the banking cost are paid.
- Cord Blood Banking collects stem cells from the umbilical cord during children.
- While the umbilical cord and cord blood are the most popular sources of stem cells, the placenta, amniotic sac, and amniotic fluid are also rich in stem cells.
Cord Blood Banking
It is the process of collecting life-saving stem cells from the placenta and umbilical cord and them storing them for use in the future.
These banks store and maintain these cord blood for future use and they charge the price for it. Depending upon the plans for storage, they charge annually or Long term fee. For example, long-term fees for 21 years are about 40000 to 60000, or yearly fees about 4000-6000, etc.
Stem cell Therapy
Stem cell banks in India
- LifeCell International Pvt. Ltd.
- Reliance Life Sciences Pvt. Ltd.
- Ree Laboratories Pvt. Ltd.
- Regenerative Medical Services Pvt. Ltd.
- CryoViva Biotech India Pvt. Ltd.
- Cryobanks International India Pvt. Ltd.
- Unistem BioSciences Pvt. Ltd.
- Totipotentrx Cell Therapy Pvt. Ltd.